46221 leans Republican by roughly 16 points: about 42% of voters vote Democratic and 58% Republican.
About 56% of adults in 46221 typically vote, below the U.S. average of about 62%. Among adults in 46221, ~24% vote Democratic, ~32% Republican, and ~44% don't vote. The map below shows estimated turnout by block group.
How 46221 compares
Among zip codes within 15 miles, 46221 leans more Republican than 29 of 40 neighbors.
Politically, 46221 sits close to the rest of Indiana.
Politics vary noticeably by block within 46221. The northeast side runs the most Democratic (D+5) and the west side runs the most Republican (R+29), a spread of about 33 points.
Why 46221 leans the way it does
This analysis examined 14,881 data points per zip code to find what predicts political lean and turnout. The items below are a few correlations that stood out for 46221, not a ranked or complete list of what matters most.
46221 votes Republican even though it is densely developed (about 79%, far above the Indiana average of 25%). State and regional patterns outweigh the Democratic lean that density usually predicts here. Low college attainment predicts Republican voting, and 46221 sits in the bottom quarter (about 16%, below 77% of zip codes).
High-school completion, developed land, and voter turnout
Places that combine low high-school-completion share and a heavily developed built environment tend to turn out at a lower rate, as 46221, IN does.
Why turnout in 46221 looks the way it does
Areas with limited routine healthcare access turn out at lower rates. 46221 is in the bottom quarter nationally for routine-care measures such as insurance coverage, preventive screenings, and dental visits. Renters vote less often than owners, and about 37% of households in 46221 rent, above 84% of zip codes. Low high-school completion lines up with lower turnout, and about 85% of adults in 46221 have completed high school, below 81% of zip codes. Learn more about the findings and methodology on the political spectrum map.
Nearby Zip Codes
Zip Codes with Similar Populations
Sources and methodology
Precinct-level voting records used to fit the model come from Indiana Secretary of State, Elections, distributed by the Voting and Election Science Team. Demographic inputs come from the U.S. Census Bureau (ACS 5-year estimates and the 2020 Decennial Census). Health and environmental inputs come from the CDC (PLACES and the Environmental Justice Index). Land cover comes from the USGS and EPA. Election-day and lead-up weather come from PRISM 4km daily grids and the NOAA Global Historical Climatology Network. Mail-voting and election-administration patterns come from the MIT Election Lab's Survey of the Performance of American Elections. Block-group crime detail comes from CrimeGrade. Internet data and modeling support provided by ISPreports.org.
Modeling and analysis by the BestNeighborhood data science team. Full methodology and findings: political spectrum map.
Methodology reviewed by the BestNeighborhood data team. Last updated May 2026.