64106 is a Democratic stronghold. About 77% of voters here vote Democratic and 23% Republican.
About 39% of adults in 64106 typically vote, below the U.S. average of about 62%. Among adults in 64106, ~30% vote Democratic, ~9% Republican, and ~61% don't vote. The map below shows estimated turnout by block group.
How 64106 compares
Among zip codes within 15 miles, 64106 leans more Democratic than 73 of 84 neighbors.
64106 runs about 73 points more Democratic than Missouri as a whole. Missouri leans Republican overall, while 64106 is one of the few Democratic-leaning pockets.
Politics vary noticeably by block within 64106. The northwest side is the most Democratic-leaning (D+66) and the southwest side is the least Democratic-leaning (D+46), a spread of about 20 points.
Why 64106 leans the way it does
This analysis examined 14,881 data points per zip code to find what predicts political lean and turnout. The items below are a few correlations that stood out for 64106, not a ranked or complete list of what matters most.
Dense areas vote Democratic. About 98% of residents in 64106 live in densely developed areas, about 62 points above the U.S. average of 36%. A high never-married share predicts Democratic voting, and about 61% of adults in 64106 have never been married, above 98% of zip codes. 64106 runs against the grain of Missouri, a Democratic-leaning pocket in a Republican-leaning state.
Population density and Democratic lean
Places with high population density tend to lean Democratic; 64106, MO sits in the top tenth nationally on this measure.
Why turnout in 64106 looks the way it does
Areas with limited routine healthcare access turn out at lower rates. 64106 is in the bottom quarter nationally for routine-care measures such as insurance coverage, preventive screenings, and dental visits. Renters vote less often than owners, and about 86% of households in 64106 rent, compared to around 66% in nearby zip codes. High-crime urban areas turn out at lower rates, and 64106 sits in the top 15% on a violent-crime measure. Learn more about the findings and methodology on the political spectrum map.
Nearby Zip Codes
Zip Codes with Similar Populations
Sources and methodology
Precinct-level voting records used to fit the model come from Missouri Secretary of State, Elections, distributed by the Voting and Election Science Team. Demographic inputs come from the U.S. Census Bureau (ACS 5-year estimates and the 2020 Decennial Census). Health and environmental inputs come from the CDC (PLACES and the Environmental Justice Index). Land cover comes from the USGS and EPA. Election-day and lead-up weather come from PRISM 4km daily grids and the NOAA Global Historical Climatology Network. Mail-voting and election-administration patterns come from the MIT Election Lab's Survey of the Performance of American Elections. Block-group crime detail comes from CrimeGrade. Internet data and modeling support provided by ISPreports.org.
Modeling and analysis by the BestNeighborhood data science team. Full methodology and findings: political spectrum map.
Methodology reviewed by the BestNeighborhood data team. Last updated May 2026.