80221 leans Democratic by roughly 30 points: about 65% of voters vote Democratic and 35% Republican.
About 62% of adults in 80221 typically vote, near the U.S. average of about 62%. Among adults in 80221, ~40% vote Democratic, ~22% Republican, and ~38% don't vote. The map below shows estimated turnout by block group.
How 80221 compares
Among zip codes within 15 miles, 80221 leans more Democratic than 33 of 69 neighbors.
80221 runs about 18 points more Democratic than Colorado as a whole.
Politics vary noticeably by block within 80221. The southwest side is the most Democratic-leaning (D+45) and the northwest side is the least Democratic-leaning (D+17), a spread of about 29 points.
Why 80221 leans the way it does
This analysis examined 14,881 data points per zip code to find what predicts political lean and turnout. The items below are a few correlations that stood out for 80221, not a ranked or complete list of what matters most.
Dense areas vote Democratic. About 98% of residents in 80221 live in densely developed areas, about 61 points above the U.S. average of 36%. A high never-married share predicts Democratic voting, and about 39% of adults in 80221 have never been married, above 87% of zip codes.
Walkability and Democratic lean
Places with a highly walkable street grid tend to lean Democratic; 80221, CO sits in the top tenth nationally on this measure. A walkable street grid does not change how people vote; it mostly reflects how urban a place is.
Why turnout in 80221 looks the way it does
Areas with limited routine healthcare access turn out at lower rates. 80221 is in the bottom quarter nationally for routine-care measures such as insurance coverage, preventive screenings, and dental visits. The uninsured rate here is about 21%, about 9 points above the Colorado average of 11%. Learn more about the findings and methodology on the political spectrum map.
Nearby Zip Codes
Zip Codes with Similar Populations
Sources and methodology
Precinct-level voting records used to fit the model come from Colorado Secretary of State, Elections, distributed by the Voting and Election Science Team. Demographic inputs come from the U.S. Census Bureau (ACS 5-year estimates and the 2020 Decennial Census). Health and environmental inputs come from the CDC (PLACES and the Environmental Justice Index). Land cover comes from the USGS and EPA. Election-day and lead-up weather come from PRISM 4km daily grids and the NOAA Global Historical Climatology Network. Mail-voting and election-administration patterns come from the MIT Election Lab's Survey of the Performance of American Elections. Block-group crime detail comes from CrimeGrade. Internet data and modeling support provided by ISPreports.org.
Modeling and analysis by the BestNeighborhood data science team. Full methodology and findings: political spectrum map.
Methodology reviewed by the BestNeighborhood data team. Last updated May 2026.